Treating MRSA and superbugs with nanotechnology and nanomedicine - Healthcare Global.
We feel that this may be significant. In the last decade, there has been an enormous increase in antibiotic-resistant bacteria, such as methicillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant Enterococcus (VRE) and fluoroquinolone-resistant E. coli. Most modern antibiotics act on specific molecular targets within bacteria. This yields therapeutic specificity but allows resistance development through mutation (among other mechanisms) since the bacterial cell morphology is generally preserved. In contrast, our polymers like certain cationic host defence peptides act on the entire cellular membrane via electrostatic attraction and subsequent pore generation. This may be very important in treating MRSA.