NovaBay Pharmaceuticals Holds Successful FDA Meeting on Clinical Development of Aganocide Compound NVC-422 for Impetigo - MarketWatch.
NovaBay recently reported positive results for the use of NVC-422 topical gel in the treatment of impetigo from a 129 patient, randomized, double-blind, dose-ranging Phase 2a clinical trial. The trial showed high clinical and bacteriological efficacy of three concentrations of the drug applied ranging from 84% to 95% at end of treatment and at follow up. These response rates compare favorably to previously published results from studies of topical antibiotics, and were substantially higher than the response rate (30-50%) anticipated for placebo. The treatment was well tolerated with the few adverse events reported being mild to moderate in severity and all resolved after the end of treatment. Additionally, the response rate for all patients infected with MRSA who completed treatment was 100%.
