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Drug resistance stands still in Texas hospital

Link: Inhibitory Activities of Eleven Antimicrobial Agents and Bactericidal Activities of Vancomycin and Daptomycin against Invasive Methicillin-Resistant Staphylococcus aureus (MRSA) from 1999 through 2006 -- Holmes and Jorgensen, 10.1128/AAC.00945-07 -- Antimicrobial Agents and Chemotherapy.

We assessed MICs and MBCs of vancomycin, daptomycin and nine other antimicrobials against methicillin-resistant Staphylococcus aureus isolates from 1999 through 2006. No vancomycin, daptomycin or linezolid resistance was observed. Clindamycin, gentamicin and ciprofloxacin resistance decreased significantly. No tolerance to vancomycin or daptomycin was observed, nor was MIC creep seen.

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