daptomycin helpful with catheter infections

Link: In vitro activity of daptomycin and vancomycin lock solutions on staphylococcal biofilms in a central venous catheter model -- LaPlante and Mermel 22 (8): 2239 -- Nephrology Dialysis Transplantation.

Conclusions. Our CVC model demonstrated that 72 h of exposure to 5 mg/ml lock solutions of daptomycin (plus calcium),  /– heparin or 5 mg/ml of vancomycin plus heparin demonstrate promise in treating catheter infections with biofilm-producing S. epidermidis. Similarly, 5 mg/ml of daptomycin (plus calcium) as a lock solution shows great promise in treating S. aureus catheter infections.