NanoCrystal delivers Silver in wound care best?

Link: HighWire Press -- Medline Abstract.

Although silver has been recognised for centuries to inhibit infection its use in wound care is relatively recent. Evidence of the efficacy of the growing number of silver dressings in clinical trials, judged by the criteria of the Cochrane Collaboration, is lacking, but there are good indications for the use of silver dressings, to remove or reduce an increasing bioburden in burns and open wounds healing by secondary intention, or to act as a barrier against cross contamination of resistant organisms such as MRSA. More laboratory, and clinical data in particular, are needed to prove the value of the many silver dressings which are now available. Some confusion persists over the measurement of toxicity and antibacterial activity but all dressings provide an antibacterial action, involving several methods of delivery. Nanocrystalline technology appears to give the highest, sustained release of silver to a wound without clear risk of toxicity.

Comments

[gregg silver]

while the nanocrystalline technology certainly has merit, there is no in vivo data to suggest it is adequately reaching enough organisms in the dynamic wound environment. as an alternative, the silver nylon continuous release while being in direct contact with the wound surfaces has the replenishment capability lost when a nanocrystal becomes consumed by or covered within the wound.