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Shining a light on an alternative treatment for MRSA

Link: Shining a light

      Dr Mark Wainwright, a senior LJMU lecturer in medicinal chemistry, who has been researching the therapy for nearly 20 years, explained: “After decades of wonder drugs, man’s supremacy over the microbe is over. Over-prescription and misuse of antibacterial drugs are to blame for this rise in resistance and we urgently need to change the way in which we employ such valuable drugs.” He continued: “Photodynamic therapy could be an effective alternative treatment. If antibiotics use a sniper’s approach to killing infections, dye therapy is like a hand grenade. Bacteria and viruses have no defence against the active oxygen it releases. The Darwinian argument of ‘survival of the fittest’ doesn’t apply because all of the bacterial cells are destroyed so they can’t develop resistance to the therapy. Its low human toxicity and the local/topical application of the drugs also mean that patients have fewer side effects.” Photodynamic therapy (PDT) is a relatively straightforward and cheap therapy. It works by the topical application of light sensitive compounds (related to dyes) onto the infected area and then shining light onto it. The light causes the dye to produce a highly reactive form of oxygen in situ, which if released close enough to a bacteria or virus, kills them, halting the infection. The therapy doesn’t even require expensive lasers as the right wavelength can be provided by ordinary light sources.

Comments

Where can one go to recieve photodynamic therapy for mrsa? Please e-mail me.

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