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Dominance of H5N1 Tamiflu Resistance in Egypt

Link: Dominance of H5N1 Tamiflu Resistance in Egypt.

The WHO has said some of those who died having contracted the H5N1 virus strain showed moderate resistance to Tamiflu, the antiviral drug. The above comments on moderate resistance to Tamiflu in some of the fatal cases are cause for concern.  Since there are only four confirmed fatalities, at least half are Tamiflu resistant.  The “moderate” resistance is almost certainly due to N294S, the genetic change found in the Gharbiya cluster a year ago.  N294S was present in samples collected prior to treatment, indicating it was circulating in Egypt.

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Dear


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